PDRN Advanced Infusion Treatment

Many users notice smoother, more hydrated skin after the very first treatment — a fresh glow and softer texture within 24–48 hours. That's the micro-infusion immediately boosting hydration and waking up your skin's repair response.

Acne scar repair itself is a longer process. For visible, lasting improvement we recommend completing at least 6 treatments over 3 months. Consistency matters more than speed.

It combines precision micro-infusion with a clinically formulated scar-repair serum. The ultra-fine 24K gold needles create micro-channels in your skin, allowing the serum to reach the deeper layers where scars actually form.

The result: stimulated collagen production, improved texture, and visibly reduced scar depth over time.

Yes. The PDRN Micro-Infusion System is designed to help improve deep acne scars by stimulating collagen and supporting repair from within — regardless of how old the scar is. The fibroblasts that rebuild a scar are still alive in old scars; they've just had no signal to act.

It takes consistency, usually a full 3-month cycle of 6 treatments, and deeper or decades-old scars may want a second cycle. But the mechanism is identical regardless of age.

The needle doesn't need to travel all the way down to the scar. Intact skin is a sealed barrier that blocks almost everything you apply — that's why creams do nothing. The 0.5mm needles open microscopic channels through that barrier, and once it's open, the serum diffuses down into the dermis far more effectively than it ever could through unbroken skin (this is why micro-infusion absorbs up to ~30× better than a topical).

On top of that, collagen rebuilding is a signaling process: PDRN and growth factors delivered into the upper dermis trigger the repair cells below them to get to work, so the effect propagates deeper than the delivery point.

Longer needles would mean bleeding, pain, downtime and medical supervision — 0.5mm is precisely what makes this safe and effective to do at home.

The micro-infusion stamp uses 0.5mm needles — ideal for what's called "epidermal needling." This depth lets the serum reach the upper dermis where acne scars form, without causing pain or requiring medical supervision.

It's long enough to:

• Stimulate collagen production
• Boost cellular renewal
• Enhance absorption of active ingredients up to 30× more effectively than topical application

And short enough to avoid bleeding or downtime, making it safe for at-home use — even for beginners.

Our formula contains 0.3% PDRN — the ideal concentration for at-home use when paired with micro-infusion, which enhances absorption far beyond regular topical application.

Because the system delivers the actives directly into the upper layers of the skin:

• 0.3% delivered through micro-infusion can be more effective in practice than higher percentages applied topically
• Topical serums with higher percentages often stay mostly on the surface
• You get meaningful results while keeping the formula gentle and safe for consistent use

The 24K gold microneedles are ultra-fine — thinner than a human hair — and just 0.5mm long. Most users describe a gentle tapping or light tingling sensation, especially in more sensitive areas. No dragging, tearing, or numbing required.

The serum is fragrance-free, alcohol-free and non-comedogenic, designed specifically for delicate post-acne skin.

Yes. Both the formula and the delivery system were designed to be non-comedogenic, non-irritating, and safe for all skin types and tones. We don't use harsh acids, retinoids or bleaching agents.

If your skin is extremely reactive, we recommend a patch test on your wrist first, or consulting a dermatologist.

Most people only notice slight redness immediately after treatment, which usually fades within a few hours — at most a day. If you treat on Friday evening, your skin should look completely normal by Monday.

We always recommend doing a 24-hour patch test on your wrist before your first full treatment.

Since PDRN is derived from salmon DNA, if you have a known fish allergy we recommend not using this product, or consulting your doctor first. Your safety always comes first.

We recommend waiting until active breakouts have calmed before using the device. Using microneedles on inflamed or broken skin can lead to irritation or delayed healing.

The Micro Infusion System is designed for post-acne care — when scars and uneven texture are your main concern.

It's simple and takes 5–10 minutes:

• Prep — cleanse and pat dry. No other products on the skin.
• Attach & prime — twist a serum vial onto the needle head, hold the device upside down for about 2 minutes so the serum saturates the needles.
• Stamp & infuse — gently press the device across your skin starting at the center of the face and working outward, with about 50% overlap between stamps. Repeat 2–3 passes over scarred areas. Avoid stamping directly on active breakouts.
• Let it absorb — pat any remaining serum onto your face and neck, leave overnight, and avoid makeup or sun exposure for the next 24 hours.

Every order includes a step-by-step video guide.

We currently offer two treatment plans depending on your scar severity and goals:

• Starter Treatment — 2 Treatments (1-Month Supply): includes 2 single-use sterile needle heads + 2 PDRN serum vials. Best for first-time users, very mild acne scars, or anyone who wants to test how their skin responds.
• Acne Scar Repair Protocol — 6 Treatments (3-Month Supply): includes 6 single-use sterile needle heads + 6 PDRN serum vials. This is our recommended option for anyone serious about visibly improving acne scars, uneven texture, and scar depth.

We recommend one Micro-Infusion session every 2 weeks. This gives your skin time to recover between treatments while supporting the gradual collagen-remodeling process.

Most users should complete 3–6 treatments for more noticeable acne scar improvement, which is why the 6-Treatment Acne Scar Repair Protocol is our recommended option.

Each needle head and serum vial is designed for one treatment only. After each session, dispose of the used needle head and gently pat any remaining serum onto the treated area. A step-by-step video guide is included.

Yes — it can be safely used on the neck, lips, and most areas of the body where you want to improve texture, fade scars, or stimulate collagen. Many users apply it to:

• Post-acne scars on the back or chest
• Uneven skin on the décolleté
• Fine lines or textural irregularities on the neck or arms

For sensitive zones like lips and neck, apply with light pressure and follow the guided stamping technique. Avoid the eyelids and waterline — stay at least 1.5 inches (about 3 cm) away from the eyes. Every order includes a detailed video guide.

No special prep needed. Just cleanse your face thoroughly and make sure your hands are clean.

Optionally, apply a gentle toner or hydrating mist before starting so the serum spreads more evenly.

After each session your skin is in "recovery mode" and more receptive to anything you apply. To protect your results:

First 24 hours:

• Avoid makeup, sun exposure, and sweating (no gym, sauna, steam)
• No actives — retinol, acids, scrubs, exfoliants
• Keep skin clean and hydrated with a gentle, fragrance-free moisturizer
• Try not to touch your face

The day after:

• Wash with a mild cleanser, pat dry, moisturize
• Apply a non-comedogenic SPF if you go outside

What's normal: light redness, slight dryness or a tight feeling for a few hours. Some people see a little flaking a few days later — that's your skin renewing.

Pro tip: your skin absorbs ingredients up to 3× better after infusion, so avoid anything harsh in that window. Most people return to their full routine within 48 hours.

Yes — but with a few guidelines. Right after treatment, your skin is more permeable and more reactive.

Safe to apply:

• Hyaluronic acid or hydrating moisturizers — apply in the evening to boost hydration and support healing
• Fragrance-free, calming creams (panthenol, ceramides, Centella)

Avoid for 24–48 hours:

• Retinol (Vitamin A)
• Exfoliating acids (glycolic, lactic, salicylic)
• Vitamin C serums, scrubs or strong actives
• Anything with fragrance or alcohol

No — and you shouldn't. Each microneedle head is sterile and single-use, just like in a clinic. Reusing the same head compromises hygiene, blunts the needles, and increases the risk of irritation or infection.

We include a fresh head for every treatment, so there's nothing to guess or clean.

We don't recommend it. Ssiki™ serum was formulated specifically for micro-infusion — lightweight, fast-absorbing, and enriched with actives like PDRN, niacinamide and panthenol that are designed to penetrate through micro-channels.

Other serums may contain irritants or molecules too large to pass through — wasting the treatment or even causing sensitivity.

The collagen your skin rebuilds during treatment is a structural change to the scar — new tissue filling depth that was empty before. That's not a coating that washes off; it's your own skin remodeling from within, and that improvement holds.

What keeps changing is everything else: skin naturally ages, and new breakouts can create new scarring over time. That's why many users move to a light maintenance rhythm — about once a month — once they've reached the result they wanted, to stay ahead of new damage. You're maintaining, not redoing.

The micro-infusion device itself is not FDA-approved yet. Our manufacturer is currently in the process of obtaining FDA 510(k) clearance for the microneedle stamp, but this review takes time and is still ongoing.

The serum is FDA-listed under MoCRA, the FDA's regulation framework for cosmetic products.

Both the device and the serum are produced in an FDA-registered, GMP-certified, ISO 22716-compliant facility — sterile conditions, controlled production, and consistent quality across every batch.

Our PDRN micro-infusion system is produced using 17 fully automated production lines in a pharmaceutical-grade environment.

Each batch follows strict international standards (GMP, GMPC, ISO 22716), with raw materials sourced from world-leading suppliers and tested for purity, microbiology and safety. The facility is FDA-registered, and core processes happen in a Class 100 sterile cleanroom using ultrapure medical-grade water.

Absolutely. Scarring affects everyone, and the system was designed for all genders and skin types. We see strong results with men who want to improve skin texture and feel confident again — without a 10-step routine or clinic visits.

Yes, but with timing in mind:

• Wait at least 2 weeks after fillers or Botox
• Wait 4–6 weeks after laser treatments

If you're under clinical care, check with your dermatologist first.

Creams sit on the surface — they can't reach the dermis where scars actually live. Rollers create micro-injuries but don't deliver any ingredients into the skin.

Ssiki™ system does both at once: it opens micro-channels and infuses a clinically active serum directly where the scars form. Plus:

• Our heads are sterile and single-use — rollers are often reused, which increases the risk of irritation and bacteria
• The stamping mechanism is more precise and less damaging than a roller's drag

If you're not satisfied with your purchase, you can return the item within 90 days of receipt for a full refund.

Email our customer service team at support@ssiki.com to start the return process. Once we receive the returned item, we'll process your refund within 5–7 business days.